SINGLE-CELL RNA SEQUENCING UNVEILS THE ACTIVATION OF EGR1-ATF3 SIGNALING IN EGR1 + MUSCLE STEM CELLS DURING HUMAN PARAVERTEBRAL MUSCLE DEGENERATION

Single-cell RNA sequencing unveils the activation of EGR1-ATF3 signaling in EGR1 + muscle stem cells during human paravertebral muscle degeneration

Background: Paravertebral muscles (PVM) degeneration (PMD) is closely associated with low back pain.Muscle stem cells (MuSCs) can promote muscle regeneration and repair.However, our understanding of the cellular composition of PVM and the key genes-mediated MuSCs functions is limited.Methods: We analyzed cells heterogeneity and identified key genes

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Development of High-Calcium Chicken Nuggets Fortified with Various Citric Acid - Extracted Chicken Eggshells Powder

Chicken nuggets are ready-to-eat frozen processed meat products that are ground, steamed, molded, coated, frozen, and fried.Because chicken nuggets have a low calcium content, it must be done with the addition of chicken eggshells powder.Chicken eggshells powder contains natural calcium in the form of calcium carbonate.The current study aims to dev

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A Journey of Change in a Comprehensive At-risk High School

It all started with 7th grade reading WASL (Washington Assessment of Student Learning, used to meet state and federal testing requirements) scores.We had just finished the annual staff meeting of humiliation in which yet another year of the results of our non-progress Dry Fruits on the annual state assessments in reading, writing and math had been

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Completing the BASEL phage collection to unlock hidden diversity for systematic exploration of phage-host interactions.

Research on bacteriophages, the viruses infecting bacteria, has fueled the development of modern molecular biology and inspired their therapeutic application to combat bacterial multidrug resistance.However, most work has so far focused on a few model phages which impedes direct applications of these findings in clinics and suggests that a vast pot

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